RS 67333 hydrochloride
CAS No. 168986-60-5
RS 67333 hydrochloride ( RS 67333 HCl; RS 67333 (hydrochloride) )
Catalog No. M27698 CAS No. 168986-60-5
potent and highly selective 5-HT4 partial agonist.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
5MG | 65 | Get Quote |
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10MG | 110 | Get Quote |
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25MG | 259 | Get Quote |
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50MG | 407 | Get Quote |
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100MG | 599 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameRS 67333 hydrochloride
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NoteResearch use only, not for human use.
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Brief Descriptionpotent and highly selective 5-HT4 partial agonist.
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Descriptionpotent and highly selective 5-HT4 partial agonist.(In Vitro):RS 67333 hydrochloride exhibits affinities for the sigma 1 (pKi = 8.9) and sigma 2 (pKi = 8.0) binding sites. At the 5-HT4 receptor mediating relaxation of the carbachol-precontracted oesophagus, RS 67333 hydrochloride acts as a potent (pEC50 of 8.4), partial agonists (intrinsic activities, with respect to 5-HT is 0.5) with respect to 5-HT .
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SynonymsRS 67333 HCl; RS 67333 (hydrochloride)
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PathwayOthers
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TargetOther Targets
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Recptorc-Fgr;Lyn;Hck;Apoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number168986-60-5
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Formula Weight389.4
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Molecular FormulaC19H30Cl2N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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2-Amino-6-cyclopropy...
2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-triamino-6-hydroxypyrimidine.
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[2-(4-Chlorophenyl)-...
[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]acetic acid?is an anti-inflammatory thiazole.
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FG 7142
FG 7142?also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM).?FG 7142?can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex.?FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM).?