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RS 67333 hydrochloride
CAS No. 168986-60-5
RS 67333 hydrochloride ( RS 67333 HCl; RS 67333 (hydrochloride) )
Catalog No. M27698 CAS No. 168986-60-5
potent and highly selective 5-HT4 partial agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 65 | Get Quote |
|
| 10MG | 110 | Get Quote |
|
| 25MG | 259 | Get Quote |
|
| 50MG | 407 | Get Quote |
|
| 100MG | 599 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRS 67333 hydrochloride
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NoteResearch use only, not for human use.
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Brief Descriptionpotent and highly selective 5-HT4 partial agonist.
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Descriptionpotent and highly selective 5-HT4 partial agonist.(In Vitro):RS 67333 hydrochloride exhibits affinities for the sigma 1 (pKi = 8.9) and sigma 2 (pKi = 8.0) binding sites. At the 5-HT4 receptor mediating relaxation of the carbachol-precontracted oesophagus, RS 67333 hydrochloride acts as a potent (pEC50 of 8.4), partial agonists (intrinsic activities, with respect to 5-HT is 0.5) with respect to 5-HT .
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SynonymsRS 67333 HCl; RS 67333 (hydrochloride)
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PathwayOthers
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TargetOther Targets
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Recptorc-Fgr;Lyn;Hck;Apoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number168986-60-5
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Formula Weight389.4
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Molecular FormulaC19H30Cl2N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Weir MC, et al. Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. ACS Chem Biol. 2018 Jun 15;13(6):1551-1559.
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