RS 67333 hydrochloride ( RS 67333 HCl; RS 67333 (hydrochloride) )

Catalog No. M27698 CAS No. 168986-60-5

potent and highly selective 5-HT4 partial agonist.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	65	Get Quote
10MG	110	Get Quote
25MG	259	Get Quote
50MG	407	Get Quote
100MG	599	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

RS 67333 hydrochloride
Note

Research use only, not for human use.
Brief Description

potent and highly selective 5-HT4 partial agonist.
Description

potent and highly selective 5-HT4 partial agonist.(In Vitro):RS 67333 hydrochloride exhibits affinities for the sigma 1 (pKi = 8.9) and sigma 2 (pKi = 8.0) binding sites. At the 5-HT4 receptor mediating relaxation of the carbachol-precontracted oesophagus, RS 67333 hydrochloride acts as a potent (pEC50 of 8.4), partial agonists (intrinsic activities, with respect to 5-HT is 0.5) with respect to 5-HT .
Synonyms

RS 67333 HCl; RS 67333 (hydrochloride)
Pathway

Others
Target

Other Targets
Recptor

c-Fgr;Lyn;Hck;Apoptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

168986-60-5
Formula Weight

389.4
Molecular Formula

C19H30Cl2N2O2
Purity

>98% (HPLC)
Solubility

——
SMILES

Cl.CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Weir MC, et al. Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. ACS Chem Biol. 2018 Jun 15;13(6):1551-1559.

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